MS-BioGraphs MSA10

NameMS-BioGraphs – MSA10
Download Link
Script for Downloading All Files
Validating and Sample Code
Graph ExplanationVertices represent proteins and each edge represents the sequence similarity between its two endpoints
Edge WeightedYes
Number of Vertices1,757,323,526
Number of Edges25,236,632,682
Maximum In-Degree207,279
Maximum Out-Degree62,060
Minimum Weight98
Maximum Weight634,925
Number of Zero In-Degree Vertices6,437,984
Number of Zero Out-Degree Vertices9,926,249
Average In-Degree14.4
Average Out-Degree14.4
Size of The Largest Weakly Connected Component15,576,385,764
Number of Weakly Connected Components628,505,933
Creation DetailsMS-BioGraphs: Sequency Similarity Graph Datasets
LicenseCC BY-NC-SA
QUB IDF2223-052
Mohsen Koohi Esfahani, Sebastiano Vigna, 
Paolo Boldi, Hans Vandierendonck, Peter Kilpatrick, March 13, 2024, 
"MS-BioGraphs: Trillion-Scale Sequence Similarity Graph Datasets", 
IEEE Dataport, doi:
doi = {10.21227/gmd9-1534},
url = {},
author = {Koohi Esfahani, Mohsen and Vigna, Sebastiano and Boldi, 
Paolo and Vandierendonck, Hans and Kilpatrick, Peter},
publisher = {IEEE Dataport},
title = {MS-BioGraphs: Trillion-Scale Sequence Similarity Graph Datasets},
year = {2024} }


Underlying Graph The underlying graph in WebGraph format:
  • File: MSA10-underlying.graph, Size: 87,421,101,649 Bytes
  • File: MSA10-underlying.offsets, Size: 2,743,422,804 Bytes
  • File:, Size: 1,439 Bytes
Total Size: 90,164,525,892 Bytes
These files are validated using ‘Edge Blocks SHAs File’ as follows.
Weights (Labels) The weights of the graph in WebGraph format:
  • File: MSA10-weights.labels, Size: 58,798,062,287 Bytes
  • File: MSA10-weights.labeloffsets, Size: 2,731,563,328 Bytes
  • File:, Size: 186 Bytes
Total Size: 61,529,625,801 Bytes
These files are validated using ‘Edge Blocks SHAs File’ as follows.
Edge Blocks SHAs File (Text) This file contains the shasums of edge blocks where each block contains 64 Million continuous edges and has one shasum for its 64M endpoints and one for its 64M edge weights.
The file is used to validate the underlying graph and the weights. For further explanation about validation process, please visit the
  • Name: MSA10_edges_shas.txt
  • Size: 45,480 Bytes
  • SHASUM: 9c42e8ba057c519ae318071e63ab3ffdf992cd50
Offsets (Binary) The offsets array of the CSX (Compressed Sparse Rows/Columns) graph in binary format and little endian order. It consists of |V|+1 8-Bytes elements.
The first and last values are 0 and |E|, respectively.
This array helps converting the graph (or parts of it) from WebGraph format to binary format by one pass over (related) edges.
  • Name: MSA10_offsets.bin
  • Size: 14,058,588,216 Bytes
  • SHASUM: b42a8f6aee7c0abdd715f523238ea59acb09c24b
WCC (Binary) The Weakly-Connected Compontent (WCC) array in binary format and little endian order.
This array consists of |V| 4-Bytes elements The vertices in the same component have the same values in the WCC array.
  • Name: MSA10-wcc.bin
  • Size: 7,029,294,104 Bytes
  • SHASUM: 37f30d638341fa50ae9c73893e7cab689ef14be8
Transposed’s Offsets (Binary) The offsets array of the transposed graph in binary format and little endian order. It consists of |V|+1 8-Bytes elements. The first and last values are 0 and |E|, respectively.
It helps to transpose the graph by performing one pass over edges.
  • Name: MSA10_trans_offsets.bin
  • Size: 14,058,588,216 Bytes
  • SHASUM: 2ae765f6f79b8f41221ba0d869648d01d19bcadd
Names (tar.gz) This compressed file contains 120 files in CSV format using ‘;’ as the separator. Each row has two columns: ID of vertex and name of the sequence.
Note: If the graph has a ‘N2O Reordering’ file, the n2o array should be used to convert the vertex ID to old vertex ID which is used for identifying name of the protein in the `names.tar.gz` file.
  • Name: names.tar.gz
  • Size: 27,130,045,933 Bytes
  • SHASUM: ba00b58bbb2795445554058a681b573c751ef315
OJSON The charactersitics of the graph and shasums of the files.
It is in the open json format and needs a closing brace (}) to be appended before being passed to a json parser.
  • Name: MSA10.ojson
  • Size: 885 Bytes
  • SHASUM: 0d8c48f9297d36a628aabcd8576cb0c083607534


For the explanation about the plots, please refer to the MS-BioGraphs paper.
To have a better resolution, please click on the images.

In-Degree Distribution
Out-Degree Distribution
Weight Distribution
Vertex-Relative Weight Distribution
Degree Decomposition
Push and Pull Locality
Cell-Binned Average Weight Degree Distribution
Weakly-Connected Components Size Distribution


Related Posts

Leave a Reply

Your email address will not be published. Required fields are marked *